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Now MHRA approved in the UK. Foundayo is prescription only. We do not sell medicines, issue prescriptions or give personal medical advice.
Oral GLP-1 medicines

GLP-1 Tablets UK: Foundayo and the Wegovy Pill Compared

Two GLP-1 tablets are licensed for weight loss in the UK: Foundayo and the Wegovy pill. Foundayo starts from

Total
44.00
for a first order today at the cheapest checked pharmacy. Below is how the two tablets differ in routine, results and price.

  • Independent: Dayo does not sell medicines
  • Live prices, checked several times a day
  • Every pharmacy GPhC checked by hand
Quick answer

Foundayo (orforglipron, Eli Lilly) and the Wegovy pill (oral semaglutide, Novo Nordisk) are the UK’s two GLP-1 tablets for weight loss. Foundayo has no food or water rules. The Wegovy pill needs an eight-hour fast and a 30-minute wait. Foundayo starts from

Total
44.00
for a first order today. The Wegovy pill’s live prices are on Ogovy.

Live Foundayo prices by dose

The lowest delivered price for one month at each dose, for a first order, across every pharmacy Dayo checks. No pharmacy is named here, so none gets a free plug. The ranked list shows who charges what.

0.8mg
Total
44.00
2.5mg
Total
63.00
5.5mg
Total
72.00
9mg
Total
90.00
14.5mg
Total
115.00
17.2mg
Total
119.00

Last checked 25 Sep 2026 at 7:12pm. Prices move through the day. See the full Foundayo price comparison for every pharmacy, repeat-order prices and codes.

The four licensed GLP-1 weight loss medicines compared

Four GLP-1 style medicines are licensed for weight loss in the UK and sold through online pharmacies. Each has its own Medstack price site, with live prices for every dose.

MedicineHow to takeMain trial resultNHS statusLive prices
Mounjarotirzepatide, Eli LillyPen, once a week20.9% average weight loss on 15mg over 72 weeks (SURMOUNT-1)NICE TA1026, phased NHS roll-outMounjaro prices
Wegovy injectionsemaglutide, Novo NordiskPen, once a week14.9% average weight loss on 2.4mg over 68 weeks (STEP 1)NICE TA875, specialist weight servicesWegovy injection prices
Wegovy pilloral semaglutide, Novo NordiskTablet, once a day before foodAbout 14% average weight loss on 25mg over 64 weeks (OASIS 4)Not on the NHS yet, NICE review to followWegovy pill prices
Foundayoorforglipron, Eli LillyTablet, once a day, no food rules11.2% average weight loss on the top trial dose over 72 weeks (ATTAIN-1)NICE appraisal ID6516 under wayPrice list here

Trial figures are averages from separate placebo-controlled trials with different people, lengths and doses. They do not rank one medicine above another. Your prescriber will advise on the right choice for you.

What a GLP-1 tablet is

GLP-1 medicines copy a gut hormone released after eating. The hormone slows the stomach and tells the brain you are full. Injections such as Mounjaro and Wegovy were the first to reach the market. Tablets arrived in the UK in 2026.

Foundayo

Orforglipron is a small molecule, not a protein. Stomach acid leaves the molecule intact, so the tablet works without a fasting routine.

What is Foundayo?

Wegovy pill

Oral semaglutide is the same protein as the Wegovy injection, paired with an absorption enhancer. Food blocks absorption, so the tablet needs an empty stomach.

Daily routine side by side

FoundayoWegovy pill
How oftenOnce a dayOnce a day
Food rulesNoneEight-hour fast before
Wait after doseNone30 minutes before food, drink or other tablets
Time of dayAny timeFirst thing, before breakfast
Dose stepsSixFour

See how to take Foundayo for the full routine.

Trial results

No trial has put the two tablets head to head. Each was tested against a placebo:

  • Foundayo (ATTAIN-1): 11.2% average weight loss on the top dose over 72 weeks, against 2.1% on placebo, in 3,127 adults.
  • Wegovy pill (OASIS 4): about 14% average weight loss on 25mg over 64 weeks, against about 2% on placebo, in 307 adults.

The trials differ in size, length and the people enrolled, so the figures do not rank the tablets. The most common side effects for both are nausea, diarrhoea, constipation and vomiting, mostly in the first weeks of each dose step. See Foundayo vs Wegovy pill for more.

NHS status

Neither tablet is on the NHS yet. NICE is appraising Foundayo under reference ID6516, with guidance expected in November 2026. The Wegovy pill awaits its own NICE review. Until then both are available privately through UK online pharmacies after a health check. Check your eligibility with our BMI and Foundayo eligibility guide.

How Dayo checks prices

Dayo is run by Medstack Ltd, an independent UK company (Companies House 16439872). We do not sell, prescribe or dispense medicines. Prices are checked against each pharmacy’s own checkout several times a day and shown as the delivered total for one month. Every pharmacy’s certificates are checked by hand before listing. Some links earn a referral fee. Fees never change the order of the price table.

GLP-1 tablet questions

What GLP-1 tablets are available in the UK?

Two: Foundayo (orforglipron) from Eli Lilly and the Wegovy pill (oral semaglutide) from Novo Nordisk. Both are daily tablets licensed for weight management.

Which GLP-1 tablet is easier to take?

Foundayo. You take the tablet once a day at any time, with or without food. The Wegovy pill needs an eight-hour fast, a sip of water and a 30-minute wait before eating or drinking.

How much do GLP-1 tablets cost in the UK?

Dayo shows the live delivered price for every Foundayo dose, and Ogovy shows the same for the Wegovy pill. The starting dose is the cheapest for both, and the price rises at each step.

Are GLP-1 tablets as good as injections?

In separate trials, the injections produced larger average weight loss. The Wegovy pill at 25mg came close to the Wegovy injection. Your prescriber will help you weigh results against routine and price.

Are GLP-1 tablets on the NHS?

Not yet. NICE is appraising Foundayo, with guidance expected in November 2026. The Wegovy pill awaits its NICE review.

Is switching from an injection to a GLP-1 tablet possible?

Yes, with a prescriber’s agreement. The prescriber sets the starting dose of the tablet based on your current injection dose and how you have responded.

Weight loss medicine guides across the Medstack sites

Each Medstack site covers one medicine in depth. These four guides compare the whole market from a different angle.

Health compare UK on every Medstack site: Monj · iGovy · Ogovy · Dayo.

More on Dayo:Foundayo retail prices, Cheapest Foundayo UK, Foundayo vs Mounjaro.

Sources

  1. Wharton S et al. Orforglipron, an oral small-molecule GLP-1 receptor agonist for obesity treatment (ATTAIN-1). New England Journal of Medicine, 2025
  2. Wharton S et al. Oral semaglutide at a dose of 25 mg in adults with overweight or obesity (OASIS 4). New England Journal of Medicine, 2025
  3. Medicines and Healthcare products Regulatory Agency. First GLP-1 tablet for weight loss approved in the UK, GOV.UK
  4. Jastreboff AM et al. Tirzepatide once weekly for the treatment of obesity (SURMOUNT-1). New England Journal of Medicine, 2022
  5. General Pharmaceutical Council. Register of pharmacies
  6. Medicines and Healthcare products Regulatory Agency. Yellow Card reporting scheme